The type of drug interaction where two drugs together have a more intense combined effect is known as?

The term that describes the interaction where two drugs produce a more intense combined effect is synergism. In pharmacology, synergistic interactions occur when the effects of two drugs taken together are greater than the sum of their individual effects. This means that rather than merely adding their effects together (which would be the case in an additive interaction), the drugs enhance one another's effects, resulting in a heightened response.

For example, if Drug A has a certain level of efficacy on its own, and Drug B has its own effect, when used together in synergy, the resulting effect can be significantly greater than just adding their effects together. This principle is important in developing combination therapies, as it can lead to enhanced efficacy at lower doses of each drug, potentially reducing side effects and improving patient outcomes.

The other terms, such as adverse reaction, describe harmful effects rather than beneficial ones; augmentation generally refers to enhancing the effect but not necessarily in a way that defines a specific interaction like synergism; and antagonism involves two drugs that oppose each other's effects, reducing overall efficacy.