What is an important consideration when taking alendronate (Fosamax)?

When taking alendronate (Fosamax), it is crucial to take it with a full glass of water. This is important for several reasons. Firstly, taking the medication with water helps ensure that the drug reaches the stomach effectively and reduces the risk of esophageal irritation, which can occur if the pill gets lodged in the esophagus. Additionally, alendronate is better absorbed when taken with plain water, as certain beverages can affect its effectiveness.

It's also worth noting that after taking alendronate, patients are advised to stay upright for at least 30 minutes and to avoid lying down, a recommendation that supports proper swallowing and absorption. This regimen is designed to enhance the drug's efficacy and minimize potential gastrointestinal side effects.