Which antihypertensive medication is available as a transdermal delivery system?

Clonidine is the antihypertensive medication that is available as a transdermal delivery system. This unique delivery method enables the medication to be absorbed through the skin over a prolonged period, which can help maintain steady drug levels in the bloodstream and enhance patient compliance by reducing the frequency of dosing.

This mode of administration can be particularly beneficial for patients who may have difficulty remembering to take oral medications or for those who experience gastrointestinal absorption issues. The transdermal patch allows for consistent medication delivery, reducing the peaks and troughs commonly associated with oral forms of medication.

In contrast, the other medications listed, such as lisinopril, amlodipine, and losartan, are primarily available in oral dosage forms and do not offer transdermal options. This highlights the distinct advantage of clonidine's transdermal formulation, making it suitable for specific patient needs and therapeutic strategies in managing hypertension.