Which dosage form is specifically designed to dissolve in the intestine rather than the stomach?

Enteric-coated tablets are specifically designed to dissolve in the intestine rather than the stomach due to the protective coating that surrounds them. This coating is made from materials that resist the acidic environment of the stomach, ensuring that the medication does not release its active ingredients until it reaches the more neutral pH found in the intestinal tract. This can be particularly important for medications that are sensitive to stomach acid, would irritate the stomach lining, or are intended to be absorbed primarily in the intestine for better therapeutic effect.

Other dosage forms, such as sublingual tablets, are intended to dissolve quickly under the tongue for rapid absorption into the bloodstream, bypassing the gastrointestinal tract altogether. Extended-release formulations are designed to release their active ingredients slowly over time, and oral syrups are liquid formulations that are swallowed and dissolved in the stomach rather than being targeted for intestinal release.