Which medication is known to possibly result in precipitate when mixed with D5W or NS?

Diazepam (Valium) is known to potentially form precipitate, especially when mixed with dextrose 5% in water (D5W) or normal saline (NS). This is due to diazepam's property of being poorly soluble in such aqueous solutions, leading to the formation of a precipitate. When diazepam is administered, it is typically mixed with appropriate solvents that enhance its solubility to prevent any complications, as precipitate formation can lead to complications during intravenous administration.

In contrast, Ativan (lorazepam) is usually more soluble in the types of solutions mentioned and is less likely to cause precipitates. Furosemide may have solubility concerns but is generally not associated with precipitate formation in D5W or NS. Gentamicin, an aminoglycoside antibiotic, is also soluble in these fluids and does not typically lead to precipitate formation. Therefore, the unique chemical properties of diazepam regarding solubility make it the medication most notorious for forming precipitate in these particular solutions.